FAM12B Products

Description

Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg.Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen.Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existingcomponents and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes aresynthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come intocontact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster aresynthesized and secreted by epididymal epithelial cells. (provided by RefSeq)

Bioinformatics

Entrez	64184 Human
Uniprot	NP_071755 Human P56851 Human
Product By Gene ID	64184
Alternate Names	epididymal protein 3B epididymal secretory protein E3 beta epididymal secretory protein E3-beta FAM12B HE3B HE3-BETA human epididymis-specific 3 beta human epididymis-specific protein 3-beta member B (epididymal) UNQ6412/PRO21187