PTGER4/EP4 Antibody - BSA Free

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3890] - Colon, Carcinoma

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3890] - Analysis of anti-PTGER4 / EP4 antibody with human colon, ganglion at 2 ug/ml.

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3890] - Human Lung, Adenocarcinoma tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3890] - Human Prostate, Carcinoma tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3890] - Human prostate, benign prostatic hyperplasia tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3890] - Human Pancreas, Carcinoma tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3890] - Breast, Carcinoma

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3890] - Brain, Glioblastoma

• Reactivity: Hu, Bv, Pm, Pm, Ca, Pm, Eq, Rb
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

PTGER4/EP4 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 15 amino acid peptide from C-terminus of human PTGER4/EP4.
• Epitope: C-terminal domain of human
• Specificity: Human PTGER4/EP4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Equine (93%), Canine (93%), Rabbit (93%), Chimpanzee (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTGER4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 2 - 3 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Mouse (87%), Rat (87%), Hamster (87%), Bat (87%), Opossum (87%), Zebrafish (87%), Turkey (80%), Chicken (80%), Xenopus (80%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PTGER4/EP4 Antibody - BSA Free

• EP4
• EP4R
• MGC126583
• PGE receptor EP4 subtype
• PGE receptor, EP4 subtype
• PGE2 receptor EP4 subtype
• prostaglandin E receptor 4 (subtype EP4)
• prostaglandin E2 receptor EP4 subtype
• Prostanoid EP4 receptor
• PTGER2
• PTGER4

Background

Prostaglandin E receptor EP4 is a Prostanoid Receptor with a relaxing effect on smooth muscle. It may play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. EP4 has been reported to be expressed in blood, colon, immune tissue, intestine, kidney, lung, ovary, skin, and uterus. ESTs have been isolated from a wide range of human tissue libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PTGER4/EP4 Antibody (NLS3890)(2)

Publications using NLS3890

• Ukon y, Nishida M, yamamori N et al. Prostaglandin EP4 Selective Agonist AKDS001 Enhances New Bone Formation by Minimodeling in a Rat Heterotopic Xenograft Model of Human Bone Frontiers in Bioengineering and Biotechnology 2022-03-17 [PMID: 35372320] (IHC-P, Human)
• Oll M, Baumann C, Behbahani TE et al. Identification of prostaglandin receptors in human ureters. BMC Urol 2012-12-10 [PMID: 23227994] (Human)

Bioinformatics

• Gene Symbol: PTGER4
• Entrez:
  • 5734(Human)