ERAS Antibody (OTI2C6)

Product Discontinued

ERAS Antibody (OTI2C6) Summary

• Immunogen: Full length recombinant protein of human ERAS (NP_853510) produced in HEK293T cells.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: ERAS
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Western Blot 1:2000
• Theoretical MW: 25.1 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 1.0% BSA and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for ERAS Antibody (OTI2C6)

• Embryonic stem cell-expressed Ras
• E-Ras
• ES cell expressed Ras
• HRAS2MGC126693
• HRASPGTPase ERas
• MGC126691
• small GTPase protein E-Ras
• v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2
• v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene

Background

ERAS belongs to the small GTPase superfamily. Ras family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. The ERas gene is expressed in embryonic stem (ES) cells and promotes their in vitro proliferation and tumorigenicity. ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ERAS
• Entrez:
  • 3266(Human)