ER alpha/NR3A1 Antibody (ESR1/420) [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow
Clone
ESR1/420
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

ER alpha/NR3A1 Antibody (ESR1/420) [DyLight 350] Summary

Immunogen
Recombinant human ESR1 protein (aa290-560)
Localization
Nucleus
Marker
Marker of Estrogen Dependence
Specificity
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa300-550. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
ESR1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ER alpha/NR3A1 Antibody (ESR1/420) [DyLight 350]

  • ER alpha
  • ER
  • Era
  • ER-alpha
  • ESR1
  • ESRESRA
  • Estradiol receptor
  • estrogen receptor 1
  • estrogen receptor alpha delta 3*4,56,7*/819-2 isoform
  • estrogen receptor alpha delta 4 +49 isoform
  • estrogen receptor alpha delta 4*5,6,7*/654 isoform
  • estrogen receptor alpha
  • estrogen receptor
  • NR3A1
  • NR3A1DKFZp686N23123
  • Nuclear receptor subfamily 3 group A member 1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ESR1
Entrez