EOMES Antibody (644730) [Alexa Fluor® 750] Summary
E. coli-derived recombinant human EOMES
Accession # O95936
Detects human EOMES in direct ELISAs.
In direct ELISAs, no cross-reactivity
with recombinant human (rh) Brachyury, rhEOMES (aa 1-115), recombinant mouse
EOMES (aa 1-126), rhTBX2, 3, 5, 6, 18, or 20 is observed.
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.
Packaging, Storage & Formulations
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
0.09% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for EOMES Antibody (644730) [Alexa Fluor® 750]
- eomesodermin (Xenopus laevis) homolog
- t box, brain, 2
- T-box brain protein 2
- T-box brain2
- TBR2eomesodermin homolog
EOMES (Eomesodermin; Eo from Greek meaning “dawn”/early in mesoderm; also TBR2) is a 72 kDa member of the TBR1 subfamily, T-box family of transcription factors. It is expressed in NK and CD8+ T cells, where CTLA4 activation suppresses EOMES activation of IFN-gamma and granzyme B genes. It is also found in the embryo, where it occurs in forebrain floorplate and migrating neuroblasts at 12.5 weeks gestation. Notably, it is reported to undergo intercellular transfer in fetal Xenopus tissue destined to become mesoderm. Here, it synchronizes a multicellular commitment to a cell lineage.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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