Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (A7L6) [PerCP]

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Product Details

Summary
Reactivity Hu, Mu, Po, Fi, PmSpecies Glossary
Applications Flow
Clone
A7L6
Clonality
Monoclonal
Host
Rat
Conjugate
PerCP

Order Details

Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (A7L6) [PerCP] Summary

Immunogen
Murine EHS laminin preparation
Localization
Basement membrane
Specificity
This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
HSPG2
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (A7L6) [PerCP]

  • basement membrane-specific heparan sulfate proteoglycan core protein
  • endorepellin (domain V region)
  • Endorepellin
  • heparan sulfate proteoglycan 2
  • HSPG
  • HSPG2
  • perlecan proteoglycan
  • Perlecan
  • PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia)
  • PRCAN
  • SJA
  • SJS
  • SJS1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47695AF350
Alexa Fluor 405 NBP2-47695AF405
Alexa Fluor 488 NBP2-47695AF488
Alexa Fluor 532 NBP2-47695AF532
Alexa Fluor 594 NBP2-47695AF594
Alexa Fluor 647 NBP2-47695AF647
Alexa Fluor 700 NBP2-47695AF700
Alexa Fluor 750 NBP2-47695AF750
Allophycocyanin NBP2-47695APC
Biotin NBP2-47695B
DyLight 350 NBP2-47695UV
DyLight 405 NBP2-47695V
DyLight 488 NBP2-47695G
DyLight 550 NBP2-47695R
DyLight 594 NBP2-47695DL594
DyLight 650 NBP2-47695C
DyLight 680 NBP2-47695FR
DyLight 755 NBP2-47695IR
FITC NBP2-47695F
HRP NBP2-47695H
Janelia Fluor 549 NBP2-47695JF549
Janelia Fluor 646 NBP2-47695JF646
PE NBP2-47695PE
PerCP NBP2-47695PCP

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Bioinformatics Tool for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695PCP)

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Diseases for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695PCP)

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Bioinformatics

Gene Symbol HSPG2