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321-FL) is immobilized at 5 µg/mL (100 µL/well), Recombinant Human Endorepellin/Perlecan (Catalog # 2364-ER) binds with an ED50 of 0.75-6 µg/mL." class="big_lightbox" target="_blank">
Perlecan is an extracellular matrix proteoglycan. It has a large core protein of 400-450 kDa and is often produced with heparan sulfate side chains. Perlecan is found in basement membranes where it contributes to the permeability characteristics, serves as a substrate for vascular cells and binds growth factors involved in vascular remodeling (2).