Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (A7L6) [Alexa Fluor® 488]

Images

 
There are currently no images for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mu, Po, Fi, MkSpecies Glossary
Applications Flow, IHC-P
Clone
A7L6
Clonality
Monoclonal
Host
Rat
Conjugate
Alexa Fluor 488

Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (A7L6) [Alexa Fluor® 488] Summary

Immunogen
Murine EHS laminin preparation
Localization
Basement membrane
Specificity
This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
HSPG2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody shomld be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (A7L6) [Alexa Fluor® 488]

  • basement membrane-specific heparan sulfate proteoglycan core protein
  • endorepellin (domain V region)
  • Endorepellin
  • heparan sulfate proteoglycan 2
  • HSPG
  • HSPG2
  • perlecan proteoglycan
  • Perlecan
  • PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia)
  • PRCAN
  • SJA
  • SJS
  • SJS1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-84168
Species: Hu
Applications: IHC, IHC-P
NBP1-47386
Species: Hu, Mu, Rb(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, Flow-IC
NBP2-32569
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP2-22203
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
NBP2-52532
Species: Hu, Rt, Mk
Applications: WB, ELISA, Flow, IHC, IHC-P, CyTOF-ready, ICC, IF
AF6868
Species: Hu
Applications: WB, IHC
NBP1-32870
Species: Hu, Ch
Applications: WB, IHC, IHC-P, IP, KD
AF4466
Species: Hu, Mu
Applications: WB
AF4925
Species: Mu
Applications: WB, Simple Western, IHC
AF231
Species: Hu
Applications: WB, Flow, IHC, IP, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ELISA(Sta)
H00008398-D01P
Species: Hu, Mu
Applications: WB
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
AF2685
Species: Hu
Applications: WB, Simple Western, IHC
AF467
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready, ICC

Publications for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488) (0)

There are no publications for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488) (0)

There are no reviews for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Array Products

Bioinformatics Tool for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488)

Discover related pathways, diseases and genes to Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488)

Discover more about diseases related to Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488).
 

Pathways for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488)

View related products by pathway.

PTMs for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488)

Learn more about PTMs related to Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (NBP2-47695AF488).

Blogs on Endorepellin/Perlecan/Heparan Sulfate Proteoglycan

There are no specific blogs for Endorepellin/Perlecan/Heparan Sulfate Proteoglycan, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (A7L6) [Alexa Fluor® 488] and receive a gift card or discount.

Bioinformatics

Gene Symbol HSPG2
Entrez