ENDOGL1 Antibody

Western Blot: ENDOGL1 Antibody [NBP2-44323] - Analysis of HepG2 (A) and Jurkat (B) lysates (35ug protein in RIPA buffer).

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

ENDOGL1 Antibody Summary

• Description: Novus Biologicals Goat ENDOGL1 Antibody (NBP2-44323) is a polyclonal antibody validated for use in WB and ELISA. Anti-ENDOGL1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-KAKEQSGTQIRKP, from the C Terminus of the protein sequence according to NP_005098.2; NP_001138936.1.
• Specificity: This antibody is expected to recognize both reported isoforms (NP_005098.2; NP_001138936.1).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: EXOG
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 0.1 - 0.3 ug/ml
• Application Notes: Western blot: Approx 40kDa band observed in lysates of cell lines HepG2 and Jurkat (calculated MW of 41.1kDa according to NP_005098.2). Recommended concentration: 0.1-0.3ug/ml.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ENDOGL1 Antibody

• EC 3.1.30
• EC 3.1.30.-
• Endo G-like 1
• endo/exonuclease (5'-3'), endonuclease G-like
• ENDOGL1mitochondrial
• ENDOGL2
• Endonuclease G-like 1MGC125945
• ENGLA
• ENGLB
• ENGLMGC125944

Background

The ENDOGL1 gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ENDOGL1 Antibody (NBP2-44323)(1)

Publication using NBP2-44323

• Tann AW, Boldogh I, Meiss G et al. Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair. J Biol Chem 2011-09-01 [PMID: 21768646]

Bioinformatics

• Gene Symbol: EXOG
• Uniprot:
  • NP_001138936.1(Human)
  • NP_005098.2(Human)