Western Blot: EIF3D Antibody [NB100-93299] - Detection of Human eIF3D/EIF3S7 on HeLa whole cell lysate. eIF3D/EIF3S7 was not efficiently immunoprecipitated by rabbit anti-eIF3D/EIF3S7 antibody NB100-93300.
The immunogen recognized by this antibody maps to a region between residue 150 and 200 of human eukaryotic translation initiation factor 3, subunit D (eukaryotic translation initiation factor 3, subunit 7) using the numbering given in entry NP_003744.1
Immunogen affinity purified
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64 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
eukaryotic translation initiation factor 3, subunit D
translation initiation factor eIF3 p66 subunit
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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