EIF3D Products

Description

Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq]

Bioinformatics

Entrez	8664 Human 55944 Mouse
Uniprot	O15371 Human NM_003753 Human AAH00469 Human NP_003744.1 Human
Product By Gene ID	8664
Alternate Names	Eukaryotic translation initiation factor 3 subunit 7 translation initiation factor eIF3 p66 subunit eIF3d eukaryotic translation initiation factor 3 subunit D eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa MGC17258 eIF3-zeta MGC126526 eIF3-p66 EIF3S7eIF3 p66 eIF-3-zeta eukaryotic translation initiation factor 3, subunit D

Diseases related to EIF3D

Discover more about diseases related to EIF3D.

Immunologic Deficiency Syndromes
Malignant Mesothelioma
Cell Transformation, Neoplastic
Malignant Neoplasms
Neoplasms
Hiv Infections
Pleural Neoplasms
Malignant Paraganglionic Neoplasm
Mesothelioma

Pathways for EIF3D

View related products by pathway and learn more about each of the pathways below.

Translation
Cell Proliferation
Proteolysis
Meiosis
Chromosome Segregation

PTMs for EIF3D

Learn more about PTMs related to EIF3D.

Cleavage

Bioinformatics Tool for EIF3D

Discover related pathways, diseases and genes to EIF3D. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.