EB3 Antibody

Western Blot: EB3 Antibody [NB100-56441] - Analysis on 15 ug of human brain lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

EB3 Antibody Summary

• Immunogen: This antibody was developed against a synthetic peptide to a portion of the human EB3 protein.
• Specificity: In human brain, an approx. 38 kDa band is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAPRE3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.5-2 ug/ml
• Control:

  EB3 Overexpression Lysate
  Human Brain Whole Tissue Lysate (Adult Whole Normal)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS containing 0.2% gelatin
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein G purified

Alternate Names for EB3 Antibody

• EB1 protein family member 3
• EB3EBF3-S
• End-binding protein 3
• microtubule-associated protein RP/EB family member 3
• microtubule-associated protein, RP/EB family, member 3
• RP3EBF3APC binding protein

Background

EB3 is a 282 amino acid homologue of EB1, a protein known to bind APC (adenomatous polyposis coli). It has been shown to bind to tubulin in vitro and microtubules in vivo. Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle. EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAPRE3
• Entrez:
  • 22924(Human)
  • 100732(Mouse)
  • 298848(Rat)
• Uniprot:
  • Q9UPY8(Human)