Dtk/TYRO3 Antibody [Biotin] Summary
Mouse myeloma cell line NS0-derived recombinant mouse Dtk
Accession # P55144
Detects mouse Dtk in ELISAs and Western blots. In Western blots, approximately 30% cross-reactivity with recombinant human (rh) Dtk is observed and no cross-reactivity with rhAxl, recombinant mouse (rm) Axl, and rmMer is observed.
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
|Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitute at 0.2 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Dtk/TYRO3 Antibody [Biotin]
- EC 2.7.10
- EC 18.104.22.168
- TYRO3 protein tyrosine kinase
- Tyrosine-protein kinase byk
- Tyrosine-protein kinase DTK
- tyrosine-protein kinase receptor TYRO3
- Tyrosine-protein kinase RSE
- Tyrosine-protein kinase SKY
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken c-Eyk) constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to the anticoagulation factor protein S. The binding affinities for Gas6 is in the order of Axl > Dtk > Mer. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Dtk is widely expressed during embryonic development. In adults, Dtk is predominantly expressed in neurons in restricted regions of the brain.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Applications: WB, IHC, ICC
Applications: Flow, IHC, CyTOF-ready, Dual ISH-IHC
Applications: WB, Flow, IHC
Species: Hu, Mu, Ec, All-NA
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Species: Hu, Mu, Rt, Po, Bv, Ca, Eq, Fe
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P
Applications: WB, ELISA, ICC/IF, RNAi
Applications: WB, Simple Western, IHC
Species: Hu, Mu, Rt, Ye, Xp(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready, Flow-IC
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, CyTOF-ready, ICFlow
Species: Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P
Applications: WB, ELISA, Flow, IHC, IP, CyTOF-ready
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, ICC, KO
Applications: IHC, IHC-P
Applications: WB, IHC, IHC-P
Publications for Dtk/TYRO3 Antibody (BAF759) (0)
There are no publications for Dtk/TYRO3 Antibody (BAF759).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for Dtk/TYRO3 Antibody (BAF759) (0)
There are no reviews for Dtk/TYRO3 Antibody (BAF759).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for Dtk/TYRO3 Antibody (BAF759) (0)
Other Available Formats
Additional Dtk/TYRO3 Products
Bioinformatics Tool for Dtk/TYRO3 Antibody (BAF759)
Discover related pathways, diseases and genes to Dtk/TYRO3 Antibody (BAF759). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on Dtk/TYRO3