Dtk/TYRO3 Antibody (OTI2C4)

Western Blot: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TYRO3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TYRO3.

Immunocytochemistry/Immunofluorescence: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY TYRO3.

Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of paraffin-embedded Human Ovary tissue using anti-TYRO3 mouse monoclonal antibody.

Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TYRO3 mouse monoclonal antibody.

Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TYRO3 mouse monoclonal antibody.

Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-TYRO3 mouse monoclonal antibody.

Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TYRO3 mouse monoclonal antibody.

Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of paraffin-embedded Human breast tissue using anti-TYRO3 mouse monoclonal antibody.

Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of paraffin-embedded Human Kidney tissue using anti-TYRO3 mouse monoclonal antibody.

Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of paraffin-embedded Human lung tissue using anti-TYRO3 mouse monoclonal antibody.

Immunoprecipitation: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Lane 1: Negative Control Lane 2: NBP1-48039 Lane 3: NBP1-48040 Lane 4: NBP1-48041 Lane 5: NBP1-48042 Lane 6: NBP1-48043 Lane 7: NBP1-48044 Lane 8: NBP1-48045

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, IHC, IP
• Clone: OTI2C4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 1.3 mg/ml

Dtk/TYRO3 Antibody (OTI2C4) Summary

• Description: Novus Biologicals Mouse Dtk/TYRO3 Antibody (OTI2C4) (NBP1-48040) is a monoclonal antibody validated for use in IHC, WB, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Full length human recombinant protein of human TYRO3 (NP_006284) produced in HEK293T cell.
• Specificity: This antibody is specific for Homo sapiens TYRO3 protein tyrosine kinase (TYRO3).
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: TYRO3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150
  • Immunoprecipitation 2ug/500ul
  • Western Blot 1:500
• Theoretical MW: 96.7 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 1.0% BSA and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1.3 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Dtk/TYRO3 Antibody (OTI2C4)

• Brt
• BYK
• Dtk
• EC 2.7.10
• EC 2.7.10.1
• FLJ16467
• Rse
• Sky
• Tif
• TYRO3 protein tyrosine kinase
• Tyro3
• Tyrosine-protein kinase byk
• Tyrosine-protein kinase DTK
• tyrosine-protein kinase receptor TYRO3
• Tyrosine-protein kinase RSE
• Tyrosine-protein kinase SKY

Background

May be involved in cell adhesion processes, particularly in the central nervous system.In case of filovirus infection, seems to function as a cell entry factor

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TYRO3
• Entrez:
  • 7301(Human)