Dopamine D1R/DRD1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Dopamine D1 R/DRD1 Antibody [NLS44] - Anti-DRD1 / Dopamine Receptor D1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: Dopamine D1 R/DRD1 Antibody [NLS44] - Human Kidney: Formalin-Fixed Paraffin-Embedded (FFPE)

Immunohistochemistry-Paraffin: Dopamine D1 R/DRD1 Antibody [NLS44] - IHC staining of human kidney, tubules.

Immunohistochemistry-Paraffin: Dopamine D1 R/DRD1 Antibody [NLS44] - Analysis of anti-Dopamine Receptor D1 / DRD1 antibody with human kidney, tubules at dilution 7 ug/ml.

Immunohistochemistry-Paraffin: Dopamine D1 R/DRD1 Antibody [NLS44] - Anti-DRD1 / Dopamine Receptor D1 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry: Dopamine D1R/DRD1 Antibody - BSA Free [NLS44] - Immunohistochemistry of Lung, Adenocarcinoma

• Reactivity: Hu, Pm, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Dopamine D1R/DRD1 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 17 amino acid peptide from C-terminus of human Dopamine D1R/DRD1.
• Epitope: C-Terminus
• Localization: Cell membrane; multi pass membrane protein.
• Specificity: Human DRD1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Primate (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DRD1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5-10 ug/ml
• Application Notes: ICC: Does not work..
• Control:

  Dopamine D1R/DRD1 Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (100%), Gibbon (94%), Rat (88%), Porcine (88%), Sheep (82%), Hamster (82%), Bovine (82%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Dopamine D1R/DRD1 Antibody - BSA Free

• D(1A) dopamine receptor
• D1DR
• DADR
• Dopamine D1 R
• Dopamine D1 receptor
• Dopamine D1R
• dopamine receptor D1
• DRD1
• DRD1A

Background

DRD1, a Dopamine Receptor, mediates the effect of the neurotransmitter dopamine, an intermediate in the biosynthesis of noradrenaline and adrenaline. It is involved in the control of motor activity and cognitive memory. Downregulation of DRD1 leads to severe impairments in working memory and to locomotor hyperactivity, which are observed in diseases such as schizophrenia, Parkinson's disease, affective disorders, and attention deficit hyperactivity disorder. DRD1 enhances smooth muscle contraction and vasodilation in the heart. It also modulates sodium transport in the kidney and is involved in the pathogenesis of hypertension. Dopamine receptor D1 has been reported mostly in various regions of the brain. ESTs have been isolated from normal olfactory epithelium and cancerous genitourinary tract libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DRD1
• Entrez:
  • 1812(Human)
• Uniprot:
  • P21728()