Dopamine Receptor D4 Antibody

Images

 
Immunohistochemistry-Paraffin: Dopamine Receptor D4 Antibody [NLS3921] - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded ...read more
Immunohistochemistry-Paraffin: Dopamine Receptor D4 Antibody [NLS3921] - Staining of human brain, Neurons and Glia
Immunohistochemistry-Paraffin: Dopamine Receptor D4 Antibody [NLS3921] - Analysis of anti-DRD4 / Dopamine Receptor D4 antibody with human brain, glioblastoma.
Immunohistochemistry-Paraffin: Dopamine Receptor D4 Antibody [NLS3921] - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after ...read more

Product Details

Summary
Reactivity Hu, Mk, PmSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Dopamine Receptor D4 Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from C-terminus of human DRD4 / Dopamine Receptor D4.
Specificity
Human DRD4 / Dopamine Receptor D4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HTR1D (65%).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DRD4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Gorilla, Gibbon. Predicted cross-reactivity based on sequence identity: Ferret (88%), Panda (88%), Hamster (82%), Elephant (82%), Equine (82%), Porcine (82%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Dopamine Receptor D4 Antibody

  • D(2C) dopamine receptor
  • D(4) dopamine receptor
  • D4DR
  • Dopamine D4 receptor
  • dopamine receptor D4
  • seven transmembrane helix receptor

Background

Dopamine Receptor D4 (DRD4), a Dopamine Receptor, has been suggested to affect personality, substance dependence, cognition, and emotion. DRD4 binds the antipsychotic medications clozapine and spiperone. DRD4 knock-out mice are anatomically normal but display altered locomotion and sensitivity to drugs such as clozapine, cocaine, and others. The DRD4 gene contains extensive polymorphisms consisting of variable numbers of tandem repeats (VNTR) in sequences corresponding to the third cytoplasmic loop of the receptor; at least 27 different haplotypes encoding 20 different protein variants have been documented. The frequency of the different variants varies among population groups. Studies have suggested a link between VNTR and human personality traits (such as novelty seeking) and diseases (such as schizophrenia, bipolar affective disorder, and Tourette syndrome); however, considerable debates exist regarding the validity and significance of such associations. DRD4 expression has been reported in various regions of the brain as well as in adrenal gland, artery, eye, heart, kidney, placenta, spinal cord, testis, and vas deferens. ESTs have been isolated from a kidney library.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-22164
Species: Mu, Rt, Hu(-)
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
NBP1-85818
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
H00006532-D01P
Species: Hu, Mu
Applications: WB
NBP1-00178
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, PEP-ELISA
NB100-56725
Species: Hu, Mu
Applications: WB, Flow, IHC, IHC-P, IP, Flow-IC
NBP1-05767
Species: Hu, Mu, Rt, Ha, Rb
Applications: WB, Flow, IHC-P
NB110-60019
Species: Mu, Rt, Hu(-)
Applications: WB, ICC/IF, IHC
NBP2-38868
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NB300-109
Species: Hu, Mu, Rt, Dr, I, Ma
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P, ICC, IHC-FrFl
NBP1-88927
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-31386
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
NBP1-89396
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
AF1638
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC
H00003845-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IP
NBP1-88769
Species: Hu, Mu
Applications: WB, IHC, IHC-P
NB110-60017
Species: Mu, Rt, Bv(-), Ca(-), Hu(-), Po(-), Rb(-), Sh(-)
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-FrFl
NBP2-26091
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
NLS3921
Species: Hu, Mk, Pm
Applications: IHC-P

Publications for Dopamine Receptor D4 Antibody (NLS3921) (0)

There are no publications for Dopamine Receptor D4 Antibody (NLS3921).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Dopamine Receptor D4 Antibody (NLS3921) (0)

There are no reviews for Dopamine Receptor D4 Antibody (NLS3921). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Dopamine Receptor D4 Antibody (NLS3921) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Array Products

Bioinformatics Tool for Dopamine Receptor D4 Antibody (NLS3921)

Discover related pathways, diseases and genes to Dopamine Receptor D4 Antibody (NLS3921). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Dopamine Receptor D4 Antibody (NLS3921)

Discover more about diseases related to Dopamine Receptor D4 Antibody (NLS3921).
 

Pathways for Dopamine Receptor D4 Antibody (NLS3921)

View related products by pathway.

PTMs for Dopamine Receptor D4 Antibody (NLS3921)

Learn more about PTMs related to Dopamine Receptor D4 Antibody (NLS3921).
 

Research Areas for Dopamine Receptor D4 Antibody (NLS3921)

Find related products by research area.

Blogs on Dopamine Receptor D4

There are no specific blogs for Dopamine Receptor D4, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Dopamine Receptor D4 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol DRD4
Entrez