DNER Antibody [Janelia Fluor® 549]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Janelia Fluor 549

DNER Antibody [Janelia Fluor® 549] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human DNER
  Arg29-His637
  Accession # Q8NFT8
• Specificity: Detects human DNER in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 30% cross-reactivity with recombinant mouse DNER is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: DNER
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DNER Antibody [Janelia Fluor® 549]

• bet
• delta and Notch-like epidermal growth factor-related receptor
• delta/notch-like EGF repeat containing
• delta-notch-like EGF repeat-containing transmembrane
• DNER
• H_NH0150O02.1
• UNQ26
• WUGSC:H_NH0150O02.1

Background

DNER, also known as Delta and Notch-like epidermal growth factor-related receptor, is a 78.5 kDa, 737 amino acid protein and is involved in activating the NOTCH1 pathway. Current research is being conducted on diseases and disorders such as hepatitis, neuronitis and pathological gambling. The protein interacts with other proteins such as NOTCH1, APH1A, ZNF24, AP1G1, and DTX1 in Notch signaling pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DNER