DMBT1/GP340 Antibody (548031) [Alexa Fluor® 594]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
548031
Clonality
Monoclonal
Host
Rat
Conjugate
Alexa Fluor 594
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

DMBT1/GP340 Antibody (548031) [Alexa Fluor® 594] Summary

Immunogen
E. Coli-derived recombinant mouse DMBT1
Trp215-Gly420
Accession # Q60997
Specificity
Detects mouse DMBT1 in direct ELISAs. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) CD163 and rhSRCRB4D is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
DMBT1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DMBT1/GP340 Antibody (548031) [Alexa Fluor® 594]

  • CRP-ductin
  • deleted in malignant brain tumors 1 protein
  • deleted in malignant brain tumors 1
  • DMBT1
  • Ebnerin
  • FLJ61058
  • Glycoprotein 340
  • GP340
  • gp-340
  • GP340muclin
  • Hensin
  • MGC164738
  • Muclin
  • SAG
  • Salivary agglutinin
  • Surfactant pulmonary-associated D-binding protein
  • Vomeroglandin

Background

DMBT1 (deleted in malignant brain tumors 1), also called salivary agglutinin (SAG) in humans, hensin in rabbit, ebnerin in rat, and muclin, crp-ductin or vomeroglandin in mouse, is a transmembrane or secreted ~340 kDa, 2085 amino acid (aa) protein of the scavenger receptor cysteine-rich (SRCR) family. It contains several SRCR and CUB domains and a zona pellucida motif. The region used as the immunogen (aa 215-420) contains most of SRCR 2 and 3, and shares ~74% aa identity with corresponding regions of rat or human DMBT1. Several alternately spliced, glycosylated and sulfated forms exist. DMBT1 functions in mucosal immunity by binding bacterial, viral and endogenous proteins to aid clearance by macrophages. It is also thought to play a role in epithelial cell differentiation and tumor suppression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DMBT1
Uniprot