Dectin-1/CLEC7A Antibody (BD6) [PerCP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
BD6
Clonality
Monoclonal
Host
Mouse
Conjugate
PerCP

Dectin-1/CLEC7A Antibody (BD6) [PerCP] Summary

Immunogen
NIH3T3 cells expressing full length Beta-glucan receptor
Specificity
NBP1-21513 recognizes human Dectin-1, also known as beta-glucan receptor (betaGR), a C-type lectin domain family member. It is a major pathogen pattern-recognition receptor that binds beta-glucans, glucose polymers that form cell-wall components or exopolymers of yeasts, fungi and some bacteria. Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, yeast, viral and protozoan infections, as well as tumor formation. Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response. It is highly expressed on peripheral blood leukocytes and dendritic cells. Human Dectin-1 has two major (betaGR-A and betaGR-B) and several minor isoforms. betaGR-A and betaGR-B differs by the presence and absence, respectively, of a stalk region. Clone BD6 recognizes betaGR-A only.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CLEC7A
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry

Reactivity Notes

Reacts with Human.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Dectin-1/CLEC7A Antibody (BD6) [PerCP]

  • Beta-glucan receptor
  • BGR
  • CD369
  • CLEC7A
  • CLECSF12
  • CLECSF12DC-associated C-type lectin 1
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12
  • C-type lectin domain family 7 member A
  • C-type lectin domain family 7, member A
  • C-type lectin superfamily member 12
  • Dectin1
  • Dectin-1
  • DECTIN1CANDF4
  • Dendritic cell-associated C-type lectin 1
  • dendritic cell-associated C-type lectin-1
  • hDectin-1
  • lectin-like receptor 1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NBP1-21513APC
DyLight 350 Labeled NBP1-21513UV
DyLight 405 Labeled NBP1-21513V
DyLight 488 Labeled NBP1-21513G
DyLight 680 Labeled NBP1-21513FR
DyLight 755 Labeled NBP1-21513IR
PE Labeled NBP1-21513PE

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Bioinformatics

Gene Symbol CLEC7A
Entrez