DEAF1 Antibody

Western Blot: DEAF1 Antibody [NBP2-14929] - Sample (30 ug of whole cell lysate) A: NT2D1 7.5% SDS PAGE, antibody diluted at 1:3000.

• Reactivity: Hu, Mu, Rt, Pm
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

DEAF1 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human DEAF1. The exact sequence is proprietary.
• Predicted Species: Mouse (98%), Rat (98%), Primate (99%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DEAF1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:500-1:3000
• Theoretical MW: 59 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chimpanzee (100%), Chicken (89%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for DEAF1 Antibody

• deformed epidermal autoregulatory factor 1 (Drosophila)
• Nuclear DEAF-1-related transcriptional regulator
• NUDRdeformed epidermal autoregulatory factor 1 homolog
• SPNsuppressin
• Zinc finger MYND domain-containing protein 5
• ZMYND5Suppressin

Background

Transcription factor that binds to sequence with multiple copies of TTC[CG]G present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: DEAF1
• Uniprot:
  • O75398(Human)