DC-LAMP Antibody (530217) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: WB
• Clone: 530217
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

DC-LAMP Antibody (530217) [Alexa Fluor® 350] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human DC-LAMP
  Asp21-Thr381
  Accession # EAW78338
• Specificity: Detects human DC-LAMP in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human LAMP is observed.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DC-LAMP Antibody (530217) [Alexa Fluor® 350]

• CD208 antigen
• CD208
• DCLAMP
• DC-LAMP
• DCLAMPDC-lysosome-associated membrane glycoprotein
• LAMP
• LAMP3
• LAMP-3
• lysosomal-associated membrane protein 3DC LAMP
• lysosome-associated membrane glycoprotein 3
• Protein TSC403
• TSC403
• TSC403CD208

Background

DC-LAMP (dendritic cell lysosome-associated membrane protein; also CD208 and LAMP3) is a  member of the LAMP family of proteins. Mature human DC-LAMP is a 389 amino acid (aa) type I transmembrane protein. It can be variably glycosylated, and apparent sizes from 54kDa to 90 kDa have been reported. It has a 254 aa luminal N-terminus and a short 14 aa cytoplasmic tail. The molecule is found in type II pneumocytes, interdigitating DC, and various tumors. It may play a role in normal lysosome and endosome function. Over aa 21‑381, human DC-LAMP shares 72% and 55% aa sequence identity with dog and mouse DC‑LAMP, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • EAW78338()