DC-LAMP Antibody (530217) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: WB
• Clone: 530217
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594

DC-LAMP Antibody (530217) [Alexa Fluor® 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human DC-LAMP
  Asp21-Thr381
  Accession # EAW78338
• Specificity: Detects human DC-LAMP in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human LAMP is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DC-LAMP Antibody (530217) [Alexa Fluor® 594]

• CD208 antigen
• CD208
• DCLAMP
• DC-LAMP
• DCLAMPDC-lysosome-associated membrane glycoprotein
• LAMP
• LAMP3
• LAMP-3
• lysosomal-associated membrane protein 3DC LAMP
• lysosome-associated membrane glycoprotein 3
• Protein TSC403
• TSC403
• TSC403CD208

Background

DC-LAMP (dendritic cell lysosome-associated membrane protein; also CD208 and LAMP3) is a  member of the LAMP family of proteins. Mature human DC-LAMP is a 389 amino acid (aa) type I transmembrane protein. It can be variably glycosylated, and apparent sizes from 54kDa to 90 kDa have been reported. It has a 254 aa luminal N-terminus and a short 14 aa cytoplasmic tail. The molecule is found in type II pneumocytes, interdigitating DC, and various tumors. It may play a role in normal lysosome and endosome function. Over aa 21‑381, human DC-LAMP shares 72% and 55% aa sequence identity with dog and mouse DC‑LAMP, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.