CXXC1 Antibody

Immunocytochemistry/Immunofluorescence: CXXC1 Antibody [NBP1-91816] - Immunofluorescent staining of human cell line HeLa shows localization to nucleus & cytosol.

Immunohistochemistry-Paraffin: CXXC1 Antibody [NBP1-91816] - Staining of human Staining of human lymph node. shows strong nuclear positivity in non-germinal center cells.

Immunohistochemistry-Paraffin: CXXC1 Antibody [NBP1-91816] - Staining of human stomach shows nuclear and cytoplasmic positivity in glandular cells.

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

CXXC1 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: VKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQ
• Predicted Species: Mouse (99%), Rat (99%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CXXC1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  CXXC1 Protein (NBP1-91816PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for CXXC1 Antibody

• CFP1CXXC-type zinc finger protein 1
• CGBPPHD finger and CXXC domain-containing protein 1
• CpG binding protein
• cpG-binding protein
• CXXC finger 1 (PHD domain)
• CXXC finger protein 1
• DNA-binding protein with PHD finger and CXXC domain
• hCGBP
• HsT2645
• PCCX12410002I16Rik
• PHF185830420C16Rik
• SPP1
• ZCGPC1
• zinc finger, CpG binding-type containing 1

Background

Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001 (PubMed 11604496)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CXXC1