Biological Strategies: Western Blot: CtIP Antibody [NB100-79810] - Detection of Human and Mouse CtIP by Western Blot. Samples: Whole cell lysate (50 ug) from 293T, HeLa, and mouse TCMK-1 cells prepared using NETN ...read more
Independent Antibodies: Western Blot: CtIP Antibody [NB100-79810] - Detection of Human CtIP on MCF7 cell lysate (5, 15, and 50 microgram) and HeLa whole cell lysate (50 microgram) using NB100-79810. CtIP was also ...read more
The immunogen recognized by this antibody maps to a region between residue 850 and the C-terminus (residue 897) of human CtBP Interacting Protein (Retinoblastoma Binding Protein 8) using the numbering given in entry NP_002885.1 (GeneID 5932).
Immunogen affinity purified
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Retinoblastoma-interacting protein and myosin-like
Sporulation in the absence of SPO11 protein 2 homolog
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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