Western Blot: CtIP Antibody [NB100-79810] - Detection of Human CtIP on HeLa whole cell lysate using NB100-79810. CtIP was also immunoprecipitated using rabbit anti-CtIP antibody BL1913 NB100-79809.
Proximity Ligation Assay: CtIP Antibody [NB100-79810] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human ATM (NB100-271) and rabbit anti-human CtIP (NB100-79810). Image merged from DAPI (2ms) and Texas ...read more
The immunogen recognized by this antibody maps to a region between residue 850 and the C-terminus (residue 897) of human CtBP Interacting Protein (Retinoblastoma Binding Protein 8) using the numbering given in entry NP_002885.1 (GeneID 5932).
Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Chimpanzee, Primates, Common squirrel monkey, Crab-eating macaque, Olive baboon, Agile gibbon, Siamang, Bornean orangutan, Black-and-white colobus monkey and Northern white-cheeked gibbon.
Alternate Names for CtIP Antibody
DNA endonuclease RBBP8
retinoblastoma binding protein 8
Retinoblastoma-binding protein 8
Retinoblastoma-interacting protein and myosin-like
Sporulation in the absence of SPO11 protein 2 homolog
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.