Western Blot: UNC13B Antibody [NBP1-33037] - Sample (30 ug of whole cell lysate) A: 293T 5% SDS PAGE, antibody diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: UNC13B Antibody [NBP1-33037] - Analysis of methanol-fixed HeLa, using UNC13B antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with an alpha Tubulin ...read more
Immunohistochemistry-Paraffin: UNC13B Antibody [NBP1-33037] - Paraffin-embedded A549 xenograft, using antibody at 1:500 dilution.
Immunocytochemistry/ Immunofluorescence: UNC13B Antibody [NBP1-33037] - UNC13B antibody detects UNC13B protein by immunofluorescent analysis. Sample: DIV9 rat E18 primary cortical neuron cells were fixed in 4% ...read more
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Immunogen affinity purified
Alternate Names for UNC13B Antibody
homolog of rat Munc13 (diacylglycerol-binding)
protein unc-13 homolog B
unc-13 homolog B (C. elegans)
unc-13-like (C. elegans)
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information go to www.P65Warnings.ca.gov.
Publications for UNC13B Antibody (NBP1-33037)(1)
We have publications tested in 1 confirmed species: Human.
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