CS Citrate Synthase Antibody (1081813) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: IHC
• Clone: 1081813
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

CS Citrate Synthase Antibody (1081813) [Alexa Fluor® 647] Summary

• Immunogen: Synthetic Peptide
  Accession # O75390
• Specificity: Detects a synthetic peptide corresponding to residues near amino acid 400 of human CS protein in Direct ELISA.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CS Citrate Synthase Antibody (1081813) [Alexa Fluor® 647]

• citrate (Si)-synthase
• citrate synthase
• citrate synthase, mitochondrial
• CS Citrate Synthase
• EC 2.3.3
• EC 2.3.3.1

Background

Citrate Synthase (CS) is a 52kDa enzyme found in nearly all cells capable of oxidative metabolism. This enzyme is the first step of the tricarboxylic acid (TCA) cycle and is found in the mitochondrial matrix.  Citrate Synthase is commonly used as a marker for the presence of intact mitochondria. Loss of CS facilitates cytosolic glycolysis and results in epithelial-mesenchymal transition (EMT) and tumor malignancy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.