CREB5 Antibody (8A5) - Azide and BSA Free

Western Blot: CREB5 Antibody (8A5) [H00009586-M02] - CREB5 monoclonal antibody (M02), clone 8A5 Analysis of CREB5 expression in Hela S3 NE.

Immunocytochemistry/Immunofluorescence: CREB5 Antibody (8A5) [H00009586-M02] - Analysis of monoclonal antibody to CREB5 on HeLa cell. Antibody concentration 10 ug/ml.

Immunohistochemistry-Paraffin: CREB5 Antibody (8A5) [H00009586-M02] - Analysis of monoclonal antibody to CREB5 on formalin-fixed paraffin-embedded human adrenal gland. Antibody concentration 1 ug/ml.

Western Blot: CREB5 Antibody (8A5) [H00009586-M02] - CREB5 monoclonal antibody (M02), clone 8A5. Analysis of CREB5 expression in Raw 264.7.

ELISA: CREB5 Antibody (8A5) [H00009586-M02] - Detection limit for recombinant GST tagged CREB5 is approximately 0.1ng/ml as a capture antibody.

• Reactivity: Hu, Mu
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: 8A5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

CREB5 Antibody (8A5) - Azide and BSA Free Summary

• Immunogen: CREB5 (NP_001011666, 1 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MFCTSGGNSASVMSMRPVPGSLSSLLHLHNRQRQPMPASMPGTLPNPTMPGSSAVLMPMERQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKA
• Specificity: CREB5 (8A5)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CREB5
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunofluoresence, immunohistochemistry (paraffin) and ELISA.
• Control:

  HeLa Nuclear Cell Lysate

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CREB5 Antibody (8A5) - Azide and BSA Free

• cAMP response element binding protein CRE-Bpa
• cAMP response element-binding protein CRE-BPa
• cAMP responsive element binding protein 5 isoform alpha
• cAMP responsive element binding protein 5
• cAMP-responsive element-binding protein 5
• CREB-5
• CREBPA
• CRE-BPA
• cyclic AMP-responsive element-binding protein 5
• H_GS165L15.1

Background

The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CREB5 Antibody (H00009586-M02)(1)

Publication using H00009586-M02

• Xueli W, Bo H, Baokai D et al. A trio of tumor suppressor miRNA downregulates CREB5 dependent transcription to modulate neoadjuvant hormonal therapy sensitivity. Neoplasia. 2023-01-03 [PMID: 36603462]

Bioinformatics

• Gene Symbol: CREB5
• Entrez:
  • 9586(Human)
  • 231991(Mouse)
• Uniprot:
  • NP_001011666(Human)