Claudin-11 Antibody

Images

 
Orthogonal Strategies: Immunohistochemistry-Paraffin: Claudin-11 Antibody [NBP1-82470] - Analysis in human testis and pancreas tissues using NBP1-82470 antibody. Corresponding CLDN11 RNA-seq data are presented ...read more
Western Blot: Claudin-11 Antibody [NBP1-82470] - HUVEC (Human Umbilical Vein Endothelial Cells) lysate. Three dilutions were tested using the WES 12-230 kDa kit (left panel): Lanes 2-3, 1:100; Lanes 4-5, 1:50; and Lanes ...read more
Immunohistochemistry-Paraffin: Claudin-11 Antibody [NBP1-82470] - Staining of human Skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: Claudin-11 Antibody [NBP1-82470] - Staining of human Cervix shows no positivity in squamous epithelial cells as expected.
Immunohistochemistry-Paraffin: Claudin-11 Antibody [NBP1-82470] - Staining of human Pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: Claudin-11 Antibody [NBP1-82470] - Staining of human Testis shows strong membranous positivity in cells in seminiferous ducts.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Claudin-11 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: DAQAFGENRFYYTAGSSSPTHAKSAHV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CLDN11
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04 - 0.4 ug/mL
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Use in IHC-P reported in scientific literature (PMID: 25630681). WB reported in scientific literature (PMID: 26339636), and customer review.
Control Peptide
Claudin-11 Protein (NBP1-82470PEP)
Reviewed Applications
Read 1 Review rated 4
using
NBP1-82470 in the following applications:

Publications
Read Publications using
NBP1-82470 in the following applications:

  • 1 publication
  • WB
    1 publication

Reactivity Notes

Rat (89%). Human reactivity reported in scientific literature (PMID: 26339636). Mouse reactivity reported in scientific literature (PMID: 25630681).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2), 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Claudin-11 Antibody

  • claudin 11
  • Claudin11
  • Claudin-11
  • CLDN11
  • Oligodendrocyte-specific protein
  • OSP
  • OSPOTMoligodendrocyte transmembrane protein
  • OTM

Background

Oligodendrocyte specific protein belongs is a major component of central nervous system myelin that is necessary for normal CNS function. The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, and are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that the Claudin 11 protein determines the permeability between layers of myelin sheaths via focal adhesion and with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Claudin-11 Antibody (NBP1-82470)(2)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: IHC-P, WB.


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IHC-P
(1)
WB
(1)
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Human
(1)
Mouse
(1)
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Review for Claudin-11 Antibody (NBP1-82470) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NBP1-82470:
Filter by Applications
Simple Western
(1)
All Applications
Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
Simple Western Claudin-11 NBP1-82470
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4
reviewed by:
Verified Customer
Simple Western Human 06/07/2021
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Summary

ApplicationSimple Western
Sample TestedHUVEC (Human Umbilical Vein Endothelial Cells)
SpeciesHuman
LotA105899

Comments

CommentsAll test lanes utilized 0.2 mg/ml protein concentrations. The WES anti-rabbit antibody kit was used.

Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Claudin-11 Antibody (NBP1-82470) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Claudin-11 Antibody (NBP1-82470)

Discover related pathways, diseases and genes to Claudin-11 Antibody (NBP1-82470). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on Claudin-11

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Recent Reviews

4
5
0
4
1
3
0
2
0
1
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Verified Customer
06/07/2021
Application: Simple Western
Species: Human

Bioinformatics

Gene Symbol CLDN11