CHD7 Antibody (772503) [DyLight 550]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 772503
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 550

CHD7 Antibody (772503) [DyLight 550] Summary

• Immunogen: E. coli-derived recombinant human CHD7
  Ala263-Gln457
  Accession # Q9P2D1
• Specificity: Detects human CHD7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human CEBP epsilon is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CHD7
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CHD7 Antibody (772503) [DyLight 550]

• ATP-dependent helicase CHD7
• CHD7
• CHD-7
• chromodomain helicase DNA binding protein 7 isoform CRA_e
• chromodomain helicase DNA binding protein 7
• chromodomain-helicase-DNA-binding protein 7
• EC 3.6.1
• EC 3.6.4.12
• FLJ20357
• FLJ20361
• IS3
• KIAA1416KAL5

Background

Human CHD7 is a chromodomain helicase DNA-binding protein and mutations in the CHD7 gene are a major cause of CHARGE syndrome. CHARGE syndrome is a well characterized multiple-malformation syndrome with distinctive diagnostic critera. Anomalies include ocular coloboma, choanal atresia, cranial nerve defects, distinctive external and inner ear abnormalities, hearing loss, cardiovascular malformations, urogenital anomalies, and growth retardation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CHD7