CDS1 Antibody - BSA Free

Western Blot: CDS1 Antibody [NBP1-33434] - HeLa whole cell and nuclear extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with CDS1 antibody [C1C3] diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Immunohistochemistry-Paraffin: CDS1 Antibody [NBP1-33434] - Mouse stomach. CDS1 antibody [C1C3] dilution: 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min .

Western Blot: CDS1 Antibody [NBP1-33434] - Mouse tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with CDS1 antibody [C1C3] (NBP1-33434) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

• Reactivity: Hu, Mu, Rt, Po
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CDS1 Antibody - BSA Free Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human CDS1. The exact sequence is proprietary.
• Localization: Endoplasmic reticulum membrane, Multi-pass membrane protein, Endoplasmic reticulum membrane
• Predicted Species: Rat (96%), Porcine (96%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CDS1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:5000-1:20000
• Theoretical MW: 53 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for CDS1 Antibody - BSA Free

• CDP-DAG synthase 1
• CDP-DG synthase 1
• CDP-DG synthetase 1
• CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
• CDP-diacylglycerol synthase 1
• CDP-diglyceride pyrophosphorylase 1
• CDP-diglyceride synthase 1
• CDP-diglyceride synthetase 1
• CDS 1
• CDS
• CTP:phosphatidate cytidylyltransferase 1
• EC 2.7.7.41
• phosphatidate cytidylyltransferase 1

Background

Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for CDS1 Antibody (NBP1-33434)(1)

Publication using NBP1-33434

• Peng J, Sheng AL, Xiao Q et al. Single-cell transcriptomes reveal molecular specializations of neuronal cell types in the developing cerebellum J Mol Cell Biol 2019-08-19 [PMID: 30690467] (IF/IHC, Mouse)

Bioinformatics

• Gene Symbol: CDS1