Species: Hu, Rt
Applications: WB, ELISA, ICC/IF, KD
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Po
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq]
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
1040 |
Alternate Names |
- CDP-DAG synthase 1
- CDP-DG synthase 1
- CDP-DG synthetase 1
- CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
- CDP-diacylglycerol synthase 1
- CDP-diglyceride pyrophosphorylase 1
- CDP-diglyceride synthase 1
- CDP-diglyceride synthetase 1
- CDS 1
- CDS
- CTP:phosphatidate cytidylyltransferase 1
- EC 2.7.7.41
- phosphatidate cytidylyltransferase 1
|
Research Areas for CDS1
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism