CDC7 Antibody (SPM171)

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Product Details

Summary
Product Discontinued
View other related CDC7 Primary Antibodies

Order Details


    • Catalog Number
      NB120-17880
    • Availability
      Product Discontinued

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CDC7 Antibody (SPM171) Summary

Immunogen
Recombinant full length protein (Human).
Localization
Nuclear
Specificity
Cdc7 Kinase (SPM171)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CDC7
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:100-1:2000
Application Notes
IHC-P: 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 55 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
Control
HeLa Whole Cell Lysate
Human Tonsil Whole Tissue Lysate (Adult Whole Normal)
Publications
Read Publication using
NB120-17880 in the following applications:

  • WB
    1 publication

Reactivity Notes

Cross-reacts with Human.Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
10mM PBS (pH 7.4) and BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein G purified

Alternate Names for CDC7 Antibody (SPM171)

  • CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1
  • CDC7 cell division cycle 7 (S. cerevisiae)
  • CDC7
  • CDC7L1
  • CDC7L1MGC117361
  • CDC7-related kinase
  • cell division cycle 7 (S. cerevisiae)
  • cell division cycle 7 homolog (S. cerevisiae)
  • cell division cycle 7-like protein 1
  • cell division cycle 7-related protein kinase
  • EC 2.7.11.1
  • HsCdc7
  • Hsk1
  • huCdc7
  • MGC126237
  • MGC126238

Background

DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins). Cdc7 kinase was also found to be important in meiosis, checkpoint responses, maintenance of chromosome structure, and repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CDC7 Antibody (NB120-17880)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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Bioinformatics

Gene Symbol CDC7
Entrez