CD98 Antibody (IPO-T10)

Product Discontinued

CD98 Antibody (IPO-T10) Summary

• Immunogen: Native leucocytes
• Localization: Cell surface, cytoplasmic
• Specificity: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC3A2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml
  • Immunocytochemistry/ Immunofluorescence 1-2 ug/ml
  • Immunofluorescence 0.5 - 1.0 ug/ml
• Application Notes: Optimal dilution for a specific application should be determined.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for CD98 Antibody (IPO-T10)

• 4F2
• 4F2hc
• 4T2HC
• antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43,4F2HC
• CD98 antigen
• CD98 heavy chain
• CD98
• CD98HC
• CH98hc
• FRP-1
• heavy chain
• Lymphocyte activation antigen 4F2 large subunit
• MDU1antigen defined by monoclonal 4F2, heavy chain
• monoclonal 44D7
• NACAE4F2 cell-surface antigen heavy chain
• SLC3A2
• solute carrier family 3 (activators of dibasic and neutral amino acidtransport), member 2,4F2 heavy chain antigen

Background

The CD98 gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein with an alpha amylase domain. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC3A2