CD7 Antibody (T3-3A1) - Azide and BSA Free

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready, ICC/IF
Clone
T3-3A1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1.0 mg/ml

Order Details

CD7 Antibody (T3-3A1) - Azide and BSA Free Summary

Immunogen
Human T cells
Localization
Cell Surface
Marker
T-Cell Leukemia Marker
Specificity
Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CD7
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.5 - 1ug/million cells in 0.1 ml
  • CyTOF-ready
  • Immunofluorescence 0.5 - 1.0 ug/ml
Application Notes
Hu-chromosome location: 17q25.3
Theoretical MW
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4°C.
Buffer
10 mM PBS
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for CD7 Antibody (T3-3A1) - Azide and BSA Free

  • CD7 antigen (p41)
  • CD7 antigen
  • CD7 molecule
  • CD7
  • GP40T-cell surface antigen Leu-9
  • LEU-9
  • T-cell antigen CD7
  • T-cell leukemia antigen
  • Tp40
  • TP41
  • TP41p41 protein

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-54901AF350
Alexa Fluor 405 NBP2-54901AF405
Alexa Fluor 488 NBP2-54901AF488
Alexa Fluor 532 NBP2-54901AF532
Alexa Fluor 594 NBP2-54901AF594
Alexa Fluor 647 NBP2-54901AF647
Alexa Fluor 700 NBP2-54901AF700
Alexa Fluor 750 NBP2-54901AF750
Allophycocyanin NBP2-54901APC
Biotin NBP2-54901B
DyLight 350 NBP2-54901UV
DyLight 405 NBP2-54901V
DyLight 488 NBP2-54901G
DyLight 550 NBP2-54901R
DyLight 594 NBP2-54901DL594
DyLight 650 NBP2-54901C
DyLight 680 NBP2-54901FR
DyLight 755 NBP2-54901IR
FITC NBP2-54901F
Janelia Fluor 549 NBP2-54901JF549
Janelia Fluor 646 NBP2-54901JF646
PE NBP2-54901PE
PerCP NBP2-54901PCP

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Contact Information

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Bioinformatics

Gene Symbol CD7