CD45RB Antibody (MEM-55)

Product Discontinued

CD45RB Antibody (MEM-55) Summary

• Immunogen: The antibody reacts with the CD45RB antigen.
• Specificity: CD45RB is present on B-cells, a subpopulation of T-cells, monocytes, macrophages and granulocytes. This antibody reacts with a carbohydrate eptitope of CD45RB, a sialidase sensative epitope which is expressed on most PBL.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PTPRC
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 1:10-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:100-1:2000
• Application Notes: This antibody is very useful for: - Flow cytometry - Western blotting (reduced and non-reduced). - Immunoprecipitation - Immunohistochemistry. For immunohistochemistry no treatment of paraffin sections is necessary. This antibody is CyTOF ready.

Reactivity Notes

Rat

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for CD45RB Antibody (MEM-55)

• B220
• CD45 antigen
• CD45R
• CD45RB
• EC 3.1.3.48
• L-CA
• LY5
• protein tyrosine phosphatase, receptor type, C
• receptor-type tyrosine-protein phosphatase C
• T200 glycoprotein
• T200 leukocyte common antigen
• T200receptor type, c polypeptide

Background

CD45RB is an alternatively spliced form of CD45, a cell surface glycoprotein. It is expressed on peripheral B cells, T cytotoxic cells and CD4+ T cells. It has a role in cell signalling regulation through the activation of the Src family of tyrosine kinases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPRC