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CD45RB Products

Antibodies
CD45RB Antibody (PTPRC/1132)
CD45RB Antibody (PTPRC/1132)
NBP2-44846
Species: Hu, Pm(-), Rt(-)
Applications: WB, Flow, ICC/IF, IHC, ICC/IF
Host: Mouse Monoclonal
CD45RB Antibody (PTPRC/1147)
CD45RB Antibody (PTPRC/1147)
NBP2-44847
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, ICC/IF
Host: Mouse Monoclonal
Proteins
Recombinant Human CD45RB Fc C ...
Recombinant Human CD45RB Fc Chimer...
10477-CD
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, na iumlve T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from na iumlve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1.

Bioinformatics

Entrez Mouse
Product By Gene ID 5788
Alternate Names
  • B220
  • CD45 antigen
  • CD45R
  • CD45RB
  • EC 3.1.3.48
  • L-CA
  • LY5
  • protein tyrosine phosphatase, receptor type, C
  • receptor-type tyrosine-protein phosphatase C
  • T200 glycoprotein
  • T200 leukocyte common antigen
  • T200receptor type, c polypeptide

Research Areas for CD45RB

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Cytokine Research
Hematopoietic Stem Cell Markers
Immunology
Mesenchymal Stem Cell Markers
Microglia Markers
Stem Cell Markers