CD3 epsilon Antibody Summary
A synthetic peptide aa156-168 (ERPPPVPNPDYEP) from human CD3e
Cell surface and cytoplasmic
Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa.
Protein A purified
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Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS with 0.05% BSA.
0.05% Sodium Azide
Protein A purified
- Western Blot 0.5-1.0ug/ml
- Flow Cytometry 0.5-1ug/million cells
- Immunocytochemistry/Immunofluorescence 1-2ug/ml
- Immunoprecipitation 1-2ug/500ug protein lysate
Human Chromosome Location: 11q23.3
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Elephant, Gibbon, Macaque, Mole Rat, New World Monkey, Orangutan, Rhesus Monkey, Chimpanzee, Frog, Opossum and Ape.
Alternate Names for CD3 epsilon Antibody
- CD3e antigen
- CD3e antigen, epsilon polypeptide (TiT3 complex)
- CD3e molecule, epsilon (CD3-TCR complex)
- T-cell antigen receptor complex, epsilon subunit of T3
- T-cell surface antigen T3/Leu-4 epsilon chain
- T-cell surface glycoprotein CD3 epsilon chain
The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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