CD3 epsilon Products

Antibodies
CD3 epsilon Antibody (C363.29 ...
CD3 epsilon Antibody (C363.29B (YC...
NBP1-26685
Species: Mu
Applications: Flow, IHC, IHC-Fr, IHC-P, In vitro, IP, BA
Host: Rat Monoclonal
Conjugate Catalog # Availability Size Price
CD3 epsilon Antibody (145-2C1 ...
CD3 epsilon Antibody (145-2C11) [U...
MAB484
Species: Mu
Applications: Flow, IP, Cell Depl, CyTOF-reported, Tstim
Host: Hamster Monoclonal
Antibody Pairs
CD3 epsilon Antibody Pair
CD3 epsilon Antibody Pair
H00000916-AP41
Species: Hu
Applications: S-ELISA
CD3 epsilon Antibody Pair
CD3 epsilon Antibody Pair
H00000916-AP42
Species: Hu
Applications: S-ELISA
Lysates
CD3 epsilon Overexpression Ly ...
CD3 epsilon Overexpression Lysate ...
NBL1-08944
Applications: WB
Proteins
Recombinant Human CD3 epsilon ...
Recombinant Human CD3 epsilon Protein
NBP2-22752
Species: Hu
Applications: PAGE
Recombinant Human CD3 epsilon ...
Recombinant Human CD3 epsilon Protein
H00000916-P01
Species: Hu
Applications: WB, ELISA, PA
CD3 epsilon Recombinant Prote ...
CD3 epsilon Recombinant Protein An...
NBP2-38520PEP
Species: Hu
Applications: AC
RNAi
CD3 epsilon RNAi
CD3 epsilon RNAi
H00000916-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

CD3 epsilon is a subunit of CD3. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits: CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 916
Alternate Names
  • CD3e antigen
  • CD3-epsilon
  • T-cell surface glycoprotein CD3 epsilon chain
  • T-cell surface antigen T3/Leu-4 epsilon chain
  • T-cell antigen receptor complex, epsilon subunit of T3
  • T3E
  • TCRE
  • CD3e antigen, epsilon polypeptide (TiT3 complex)
  • FLJ18683
  • CD3e molecule, epsilon (CD3-TCR complex)

Research Areas for CD3 epsilon

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Apoptosis
CD Markers
Cytokine Research
Diabetes Research
Immunology
Mesenchymal Stem Cell Markers
Signal Transduction
Stem Cell Lines
Stem Cell Markers

PTMs for CD3 epsilon

Learn more about PTMs related to CD3 epsilon.

Phosphorylation
Cleavage
Methylation
Gpi Anchoring
Ubiquitination

Bioinformatics Tool for CD3 epsilon

Discover related pathways, diseases and genes to CD3 epsilon. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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