CD25/IL-2R alpha Antibody (Basiliximab) [DyLight 680] Summary
Recombinant Monoclonal Antibody.
Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Protein A purified
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- Western Blot
- Flow Cytometry
Optimal dilution of this antibody should be experimentally determined.
Packaging, Storage & Formulations
Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Protein A purified
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for CD25/IL-2R alpha Antibody (Basiliximab) [DyLight 680]
- CD25 antigen
- IL-2 R alpha
- IL-2 receptor subunit alpha
- IL2R alpha
- IL-2R subunit alpha
- interleukin 2 receptor, alpha
- interleukin-2 receptor subunit alpha
- TAC antigen
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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