CD25/IL-2R alpha Antibody (AP-MAB0710) [PE]

Product Image: CD25/IL-2R alpha Antibody (AP-MAB0710) [PE] [NB110-97867PE] - Vial of PE conjugated antibody. PE has two excitation maxima, 498 nm excited by the Blue laser (488 nm) and 565 nm excited by the Yellow-Green laser (561 nm). Both result in emission at 578 nm.

• Reactivity: Mu, Rt
• Applications: Flow, IHC, CyTOF-ready
• Clone: AP-MAB0710
• Clonality: Monoclonal
• Host: Rat
• Conjugate: PE

CD25/IL-2R alpha Antibody (AP-MAB0710) [PE] Summary

• Description: This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
• Immunogen: Mouse recombinant CD25/IL-2R alpha
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rat
• Gene: IL2RA
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 30134210).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for CD25/IL-2R alpha Antibody (AP-MAB0710) [PE]

• CD25 antigen
• CD25
• IDDM10
• IL-2 R alpha
• IL-2 receptor subunit alpha
• IL2R alpha
• IL-2R subunit alpha
• IL2R
• IL2RA
• IL-2Ra
• IL-2-RA
• IL2-RA
• interleukin 2 receptor, alpha
• interleukin-2 receptor subunit alpha
• p55
• TAC antigen
• TCGFR

Background

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.(provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD25/IL-2R alpha Antibody (NB110-97867PE)(1)

Publication using NB110-97867PE

• Izadi Z, Hajizadeh-Saffar E, Hadjati J et al. Tolerance induction by surface immobilization of Jagged-1 for immunoprotection of pancreatic islets Biomaterials Aug 10 2018 [PMID: 30134210] (Flow, Rat) Biomaterials. 2018-11-01 [PMID: 30134210] (FLOW, Rat)
  
  Details:
  Citation using the PE form of this antibody.

Bioinformatics

• Gene Symbol: IL2RA