CD1a Antibody (O10+C1A/711) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC-Fr, IHC-P
Clone
O10+C1A/711
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405

Order Details

CD1a Antibody (O10+C1A/711) [Alexa Fluor® 405] Summary

Immunogen
Human thymus cells (O10); Recombinant human CD1a protein (C1A/711)
Localization
Cell surface
Marker
Mature Langerhans Cells Marker
Specificity
At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa)
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
CD1A
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD1a Antibody (O10+C1A/711) [Alexa Fluor® 405]

  • CD1
  • CD1a antigen
  • CD1A antigen, a polypeptide
  • CD1a molecule
  • CD1a
  • cluster of differentiation 1 A
  • cortical thymocyte antigen CD1A
  • differentiation antigen CD1-alpha-3
  • epidermal dendritic cell marker CD1a
  • FCB6
  • hTa1 thymocyte antigen
  • HTA1
  • R4
  • T6
  • T-cell surface antigen T6/Leu-6
  • T-cell surface glycoprotein CD1a

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CD1a Antibody (NBP2-34698AF405) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34698AF350
Alexa Fluor 405 NBP2-34698AF405
Alexa Fluor 488 NBP2-34698AF488
Alexa Fluor 532 NBP2-34698AF532
Alexa Fluor 594 NBP2-34698AF594
Alexa Fluor 647 NBP2-34698AF647
Alexa Fluor 700 NBP2-34698AF700
Alexa Fluor 750 NBP2-34698AF750
Allophycocyanin NBP2-34698APC
Allophycocyanin/Cy7 NBP2-34698APCCY7
Biotin NBP2-34698B
DyLight 350 NBP2-34698UV
DyLight 405 NBP2-34698V
DyLight 488 NBP2-34698G
DyLight 550 NBP2-34698R
DyLight 594 NBP2-34698DL594
DyLight 650 NBP2-34698C
DyLight 680 NBP2-34698FR
DyLight 755 NBP2-34698IR
HRP NBP2-34698H
Janelia Fluor 549 NBP2-34698JF549
Janelia Fluor 646 NBP2-34698JF646
PE NBP2-34698PE
PE/Atto594 NBP2-34698PEATT594
PE/Cy5.5 NBP2-34698PECY55
PE/Cy7 NBP2-34698PECY7

Additional CD1a Products

Array NBP2-34698AF405

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Diseases for CD1a Antibody (NBP2-34698AF405)

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Calculators

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Bioinformatics

Gene Symbol CD1A