CD1a Antibody (NA1/34-HLK) - BSA Free

Images

 
Immunohistochemistry-Frozen: CD1a Antibody (NA1/34-HLK) [NB100-64852] - Immunoperoxidase staining of human tonsil cryosection using Mouse anti Human CD1a antibody followed by HISTAR detection system. Medium power
Flow Cytometry: CD1a Antibody (NA1/34-HLK) [NB100-64852] - Analysis using the FITC conjugate of NB100-64852. Staining of MOLT 4 cells.
Immunohistochemistry-Frozen: CD1a Antibody (NA1/34-HLK) [NB100-64852] - mmunoperoxidase staining of human tonsil cryosection using Mouse anti Human CD1a antibody followed by HISTAR detection system. Low power
Flow Cytometry: CD1a Antibody (NA1/34-HLK) [NB100-64852] - Analysis using the Biotin conjugate of NB100-64852. Staining of MOLT 4 cells with CD1a antibody.

Product Details

Summary
Reactivity Hu, CaSpecies Glossary
Applications Flow, IHC, IHC-Fr
Clone
NA1/34-HLK
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Order Details

CD1a Antibody (NA1/34-HLK) - BSA Free Summary

Immunogen
Human thymocytes
Specificity
NB100-64852 recognizes the human CD1a cell surface glycoprotein, a 49kD molecule expressed in association with beta 2 microglobulin. CD1a is expressed strongly by cortical thymocytes, and also by Langerhans cells and interdigitating cells.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CD1A
Purity
Ion exchange chromatography
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50-1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
Reviewed Applications
Read 1 Review rated 5
using
NB100-64852 in the following applications:

Publications
Read Publications using
NB100-64852 in the following applications:

Reactivity Notes

Species Cross Reactivity: Dog, Cynomolgus monkey Use in Canine reported in scientific literature (PMID:31837774).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Ion exchange chromatography

Alternate Names for CD1a Antibody (NA1/34-HLK) - BSA Free

  • CD1
  • CD1a antigen
  • CD1A antigen, a polypeptide
  • CD1a molecule
  • CD1a
  • cluster of differentiation 1 A
  • cortical thymocyte antigen CD1A
  • differentiation antigen CD1-alpha-3
  • epidermal dendritic cell marker CD1a
  • FCB6
  • hTa1 thymocyte antigen
  • HTA1
  • R4
  • T6
  • T-cell surface antigen T6/Leu-6
  • T-cell surface glycoprotein CD1a

Background

All CD1 molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 molecules are involved in T cell activation. In contrast to MHC, however, CD1 molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD1a Antibody (NB100-64852)(8)

We have publications tested in 1 confirmed species: Canine.

We have publications tested in 1 application: Flow.


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Flow
(1)
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Canine
(1)
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Showing Publications 1 - 8 of 8.
Publications using NB100-64852 Applications Species
Cruz P, Sosoniuk-Roche E, Maldonado I et al. Trypanosoma cruzi calreticulin: In vitro modulation of key immunogenic markers of both canine tumors and relevant immune competent cells Immunobiology. [PMID: 31837774] (Flow, Canine) Flow Canine
Sugiura, K et al. Effect of IL-12 on canine dendritic cell maturation following differentiation induced by granulocyte-macrophage CSF and IL-4. Vet Immunol Immunopathol. 2010 Jun 17. [PMID: 20599278]
Hirbod, T et al. Abundant expression of HIV target cells and C-type lectin receptors in the foreskin tissue of young Kenyan men. Am J Pathol 176: 2798-805. 2010 [PMID: 20395432]
Liu, CC et al. Transient downregulation of monocyte-derived dendritic-cell differentiation, function, and survival during tumoral progression and regression in an in vivo canine model of transmissible venereal tumor. Cancer Immunol Immunother 57: 479-91. 2008 [PMID: 17710396]
Yoshino, N et al. 2000 Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of Cynomolgus monkeys Macaca fascicularis by using anti-human cross reactive antibodies. Exp Anim 49: 97-110. 2000 [PMID: 10889948]
Galkowska, H et al. Reactivity of antibodies directed against human antigens with surface markers on canine leucocytes. Vet Immunol Immunopathol 53: 329-334. 1996 [PMID: 8969052]
Poulter, L W et al. Discrimination of human macrophages and dendritic cells by means of monoclonal antibodies. Scand J Immunol 24: 351-357. 1986 [PMID: 3529367]
McMichael, A J et al. A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur J Immunol 9: 205-210. 1979 [PMID: 376318]

Review for CD1a Antibody (NB100-64852) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Canine.

Reviews using NB100-64852:
Filter by Applications
Immunocytochemistry
(1)
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Filter by Species
Canine
(1)
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Images Ratings Applications Species Date Details
Immunocytochemistry CD1a NB100-64852
Enlarge
5
reviewed by:
A G
Immunocytochemistry Canine 06/13/2017
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Summary

ApplicationImmunocytochemistry
Sample TestedDog blood cells on slide
SpeciesCanine
Lot1609

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Recent Reviews

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A G
06/13/2017
Application: Immunocytochemistry
Species: Canine

Bioinformatics

Gene Symbol CD1A