CD-M6PR Antibody

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Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, IHC, IHC-Fr, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

CD-M6PR Antibody Summary

Immunogen
A synthetic peptide from the internal region of mouse MPRD (Cation dependent mannose-6-phosphate receptor) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat.
Specificity
MPRD.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
M6PR
Purity
IgG purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 10-50 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Mouse, rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
IgG purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized water. Add glycerol (1:1) for additional stability.

Alternate Names for CD-M6PR Antibody

  • 000 Man6PR
  • 46 kDa mannose 6-phosphate receptor
  • 46-kDa mannose 6-phosphate receptor
  • cation-dependent mannose-6-phosphate receptor
  • CD Man-6-P receptor
  • CDM6PR
  • CD-M6PR
  • CD-MPR
  • FLJ32994
  • M6PR
  • mannose-6-phosphate receptor (cation dependent)
  • MPR 46
  • MPR46
  • MPRD
  • Mr 46
  • SMPR

Background

FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.; SUBUNIT: Homodimer. Binds GGA1, GGA2 and GGA3.; SUBCELLULAR LOCATION: Lysosome membrane; Single-pass type I membrane protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol M6PR
Entrez
Uniprot