CD-M6PR Antibody - Azide and BSA Free

• Reactivity: Hu, Mu, Rt, Pm
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

CD-M6PR Antibody - Azide and BSA Free Summary

• Immunogen: A synthetic peptide from mouse CD-M6PR conjugated to blue carrier protein was used as the antigen.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: M6PR
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 10-50 ug/ml
  • Immunohistochemistry-Paraffin 10-50 ug/ml
  • Western Blot 10-50 ug/ml

Reactivity Notes

Marmoset (100%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Ammonium sulfate precipitation
• Reconstitution Instructions: Reconstitute 0.5 mg size in 0.5 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the 0.1 mg size is provided in reconstituted format.

Alternate Names for CD-M6PR Antibody - Azide and BSA Free

• 000 Man6PR
• 46 kDa mannose 6-phosphate receptor
• 46-kDa mannose 6-phosphate receptor
• cation-dependent mannose-6-phosphate receptor
• CD Man-6-P receptor
• CDM6PR
• CD-M6PR
• CD-MPR
• FLJ32994
• M6PR
• mannose-6-phosphate receptor (cation dependent)
• MPR 46
• MPR46
• MPRD
• Mr 46
• SMPR

Background

FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.; SUBUNIT: Homodimer. Binds GGA1, GGA2 and GGA3.; SUBCELLULAR LOCATION: Lysosome membrane; Single-pass type I membrane protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: M6PR
• Entrez:
  • 17113(Mouse)
  • 312689(Rat)
• Uniprot:
  • P24668(Mouse)