CCR9 Antibody (882416) [Alexa Fluor® 647]

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications Flow
Clone
882416
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 647
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

CCR9 Antibody (882416) [Alexa Fluor® 647] Summary

Immunogen
NS0 mouse myeloma cell line transfected with rat CCR9
Specificity
Detects rat CCR9 in direct ELISAs. Stains rat CCR9 transfectants but not irrelevant transfectants in flow cytometry.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CCR9
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCR9 Antibody (882416) [Alexa Fluor® 647]

  • C-C chemokine receptor type 9
  • C-C CKR-9
  • CC-CKR-9
  • CCR9
  • CCR-9
  • CD199
  • CDw199 antigen
  • CDw199
  • chemokine (C-C motif) receptor 9
  • G protein-coupled receptor 28
  • GPR28
  • GPR-9-6G-protein coupled receptor 28

Background

CCR9 is an approximately 42 kDa (predicted) seven transmembrane domain receptor for the chemokine CCL25/TECK. It is expressed on CD8+ T cells, monocytes, dendritic cells, and IgA+ plasma cells. It plays a role in oral and gut tolerance, the development of g/d T cells, and the thymic recruitment of hematopoietic progenitor cells. CCR9+ cells limit inflammatory cell infiltration in rheumatoid arthritis, hepatitis, colitis, and inflammatory bowel disease, but exacerbate it in atherosclerosis. In the brain, CCR9 is expressed on CA1 region pyramidal neurons in the hippocampus and is upregulated on microglia during T. gondii infection. CCR9 is also upregulated in a variety of cancers where it promotes tumor cell metastasis. Rat CCR9 shares 86% and 98% amino acid sequence identity with human and mouse CCR9, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional Array Products

Array FAB8287R

Bioinformatics Tool for CCR9 Antibody (FAB8287R)

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Diseases for CCR9 Antibody (FAB8287R)

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Bioinformatics

Gene Symbol CCR9