Flow, IHC, CyTOF-ready, ICC/IFHost:
Applications: Flow, CyTOF-ready, ICC/IF
Host: Mouse Monoclonal
CCR9 is encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. Two alternatively spliced transcript variants have been described.
|Product By Gene ID
- CDw199 antigen
- G protein-coupled receptor 28
- C-C chemokine receptor type 9
- GPR-9-6G-protein coupled receptor 28
- C-C CKR-9
- chemokine (C-C motif) receptor 9
Bioinformatics Tool for CCR9
Discover related pathways, diseases and genes to CCR9. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.