CCR3 Antibody

Images

 
Western Blot: CCR3 Antibody [NBP2-15764] - Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: CCR3 Antibody [NBP2-15764] - Paraffin-embedded human ovarian carcinoma. CCR3 antibody [C2C3], C-term dilution: 1:500.
Immunohistochemistry-Paraffin: CCR3 Antibody [NBP2-15764] - Paraffin-embedded human colon carcinoma. CCR3 antibody [C2C3], C-term dilution: 1:500.

Product Details

Summary
Reactivity Hu, RMSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

CCR3 Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCR3. The exact sequence is proprietary.
Localization
Cell membrane
Predicted Species
Rhesus Macaque (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCR3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CCR3 Antibody

  • b-chemokine receptor
  • CC chemokine receptor 3
  • C-C chemokine receptor type 3
  • C-C CKR-3
  • CCR3
  • CCR-3
  • CD193 antigen
  • CD193
  • chemokine (C-C motif) receptor 3
  • CKR3CC-CKR-3CMKBR3CD193
  • eosinophil CC chemokine receptor 3
  • Eosinophil eotaxin receptor
  • MGC102841

Background

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CCR3
Entrez
Uniprot