CCR10/GPR2 Antibody (248918) [mFluor Violet 500 SE]

• Reactivity: Mu
• Applications: Flow, CyTOF-ready
• Clone: 248918
• Clonality: Monoclonal
• Host: Rat
• Conjugate: mFluor Violet 500 SE

CCR10/GPR2 Antibody (248918) [mFluor Violet 500 SE] Summary

• Immunogen: C6 rat glioma cell line transfected with mouse CCR10
  Met1-Asn362
  Accession # NP_031747
• Specificity: Detects mouse CCR10. Stains mouse CCR10-transfected cells but not irrelevant transfectants.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: CCR10

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CCR10/GPR2 Antibody (248918) [mFluor Violet 500 SE]

• CC chemokine receptor 10
• C-C chemokine receptor type 10
• C-C CKR-10
• CC-CKR-10
• CCR10
• CCR-10
• chemokine (C-C motif) receptor 10
• G protein-coupled receptor 2
• GPR2
• GPR2G-protein coupled receptor 2

Background

Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28 which displays chemotactic activity for resting CD4+ and CD8+ T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCR10