CCL23/Ck beta 8-1/MIP3 Antibody (CCL23/4036)

Formalin-fixed, paraffin-embedded human adrenal gland stained with CCL23/Ck beta 8-1/MIP3 Antibody (CCL23/4036). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Analysis of Protein Array containing more than 19,000 full-length human proteins using CCL23-Monospecific Mouse Monoclonal Antibody (CCL23/4036).

• Reactivity: Hu
• Applications: IHC
• Clone: CCL23/4036
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

CCL23/Ck beta 8-1/MIP3 Antibody (CCL23/4036) Summary

• Description: Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.
• Immunogen: Recombinant fragment (around aa1-120) of human CCL23/Ck beta 8-1/MIP3 protein (exact sequence is proprietary)
• Localization: Secreted
• Isotype: IgG2c Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CCL23
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1-2ug/ml for 30 minutes at RT
• Application Notes: Immunohistochemistry-Paraffin 1-2ug/ml for 30 minutes at RT. Optimal dilution for a specific application should be determined.. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for CCL23/Ck beta 8-1/MIP3 Antibody (CCL23/4036)

• C6 beta-chemokine
• CCL23/Ck beta 8-1
• chemokine (C-C motif) ligand 23
• Ck beta 8-1
• CKb8
• Ckb-8
• Ckb81
• CK-beta-8
• hmrp-2a
• Macrophage inflammatory protein 3
• MIP3
• MIP-3CK-BETA-8
• MPIF1
• MPIF-1Ckb-8-1
• Myeloid progenitor inhibitory factor 1
• SCYA23C-C motif chemokine 23
• small inducible cytokine subfamily A (Cys-Cys), member 23
• Small-inducible cytokine A23

Background

Macrophage Inflammatory Protein 3, also known as CCL23, is located on the p-arm of chromosome 9 with other CC cytokine genes which are involved in immunoregulatory and inflammatory processes. In patients with rheumatoid arthritis, high levels on CCL23(19-99) have been found in synovial fluids. This protein is known to have interaction with CCR1, CCR10, CCR2, CCR3 and CCR4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCL23