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371-MP) chemo-attracts the BaF3 mouse pro-B cell line transfected with human CCR1 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Human CCL23/MPIF-1 (0.04 µg/mL) is neutral-ized (green line) by increasing concentrations of Goat Anti-Human CCL23/Ck beta 8-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF508). The ND50 is typically 0.15-0.75 µg/mL." class="big_lightbox" target="_blank">
Species: Hu Applications: WB, B/N Host: Goat Polyclonal
Macrophage Inflammatory Protein 3, also known as CCL23, is located on the p-arm of chromosome 9 with other CC cytokine genes which are involved in immunoregulatory and inflammatory processes. In patients with rheumatoid arthritis, high levels on CCL23(19-99) have been found in synovial fluids. This protein is known to have interaction with CCR1, CCR10, CCR2, CCR3 and CCR4.