CCL23/Ck beta 8-1/MIP3 Antibody (CCL23/4036) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: IHC
• Clone: CCL23/4036
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

CCL23/Ck beta 8-1/MIP3 Antibody (CCL23/4036) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
• Immunogen: Recombinant fragment (around aa1-120) of human CCL23/Ck beta 8-1/MIP3 protein (exact sequence is proprietary)
• Localization: Secreted
• Isotype: IgG2c Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CCL23
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for CCL23/Ck beta 8-1/MIP3 Antibody (CCL23/4036) [CoraFluor™ 1]

• C6 beta-chemokine
• CCL23/Ck beta 8-1
• chemokine (C-C motif) ligand 23
• Ck beta 8-1
• CKb8
• Ckb-8
• Ckb81
• CK-beta-8
• hmrp-2a
• Macrophage inflammatory protein 3
• MIP3
• MIP-3CK-BETA-8
• MPIF1
• MPIF-1Ckb-8-1
• Myeloid progenitor inhibitory factor 1
• SCYA23C-C motif chemokine 23
• small inducible cytokine subfamily A (Cys-Cys), member 23
• Small-inducible cytokine A23

Background

Macrophage Inflammatory Protein 3, also known as CCL23, is located on the p-arm of chromosome 9 with other CC cytokine genes which are involved in immunoregulatory and inflammatory processes. In patients with rheumatoid arthritis, high levels on CCL23(19-99) have been found in synovial fluids. This protein is known to have interaction with CCR1, CCR10, CCR2, CCR3 and CCR4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCL23